• Automatable, 96-well microplate format with fluorescence detection
• Sufficient for ~90 data points

Rapid quantitation of total sialic acid by fluorescence detection, either free or released from intact glycoproteins:

• Broad range of detection, 40 pmol - 1,000 pmol
• 96-well microplate format
• Sample digestion, conversion, detection and quantitation performed in a single well for fast and simple processing
• Enzymatic cleavage allows rapid analysis (~75 minutes or less) with minimal, if any, degradation of sialic acid
• Sufficient for ~90 data points

[TNGS300.1An Enzyme-based Sialic Acid Quantitation Assay for Rapid Screening of Therapeutic Glycoproteins During Process Development:  A Potential Process Analytical Technology]

[TNGS300.2Qualification of a Process Analytical Technology for Quantifying Sialic Acid on Therapeutic Proteins using Two Instrument Platforms]