GlykoPrep™ Rapid Glycoprotein Sample Preparation Platform
N-Glycan Sample Preparation
The distribution of N-linked glycans plays a critical role in the efficacy, immunogenicity, and pharmacokinetics of therapeutic proteins. Multi-step, multi-day , sample preparation methods have limited N-linked glycan analysis to only samples that represent critical decision points. Glycan analysis for bioreactor control, strain selection or comparability studies has never been possible.
|The GlykoPrep System
The GlykoPrep™ platform dramatically streamlines glycoprotein sample preparation. From purification to glycan release and labeling, the entire sample prep can be completed in 3 hours, not 3–4 days.
- Innovative platform can process up to 192 samples in < 3 hours
- Modular format enables seamless integration into a variety of workflows
- Rapid labeling and cleanup for quantitative data
The GlykoPrep Sample Preparation System requires minimal equipment: a centrifuge with a deep-well plate rotor (minimum 44 mm height), a Starter Labware Kit, and Heater and Incubation Blocks.
New glycoanalysis kits coming soon — call us to talk about our new product pipeline!
GlykoPrep is modular and can be integrated into any workflow, regardless of sample throughput or sample type. The GlykoPrep platform is a streamlined solution for anyone that requires rapid, quantitative glycan profiling on your current analysis platform.
- Cell culture optimization
- Strain selection
- Product characterization
- PAT assays for QbD
- QC release
- Monoclonal antibodies (purified or crude)
- Fc-fusion proteins
- Other recombinant glycoproteins
- Manual processing
- Semi-automated with liquid handling system
- Fully automated
The GlykoPrep Workflow
- Contact us for a demonstration of the GlykoPrep Rapid Glycoprotein Sample Preparation Platform
*POROS™ and MabCapture™ are registered trademarks of Life Technologies Corporation.
†Acceptable microplate centrifuge/rotor combinations must be able to 1) accept a stack of microtiter plates 44 mm high, and 2) centrifuge accurately at <50xg RCF. The centrifuge/rotor/bucket combinations listed above have these specifications.